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brain with the conversation about pain. pain serves a very important function for us to survive, it teaches us what to avoid and lets us know when to seek medical help. at the same time, though it can create tremendous suffering. st. augustine once said the greatest evil is physical pain, 100 million americans live with it every day would yo would wouo doubt agree, pain knows no boundaries, regardless of age and race, beyond the physical symptoms the experience of chronic pain often leads to feelings of isolation and hopelessness. >> laura klein had been living with pain since a knee injury in 2008 and joins me this evening to speak about her experiences and incredible group of scientists are also here to discuss how we perceive and process pain, david bar stiewk of children's hospital and david julius of the university of california, san francisco, allan basbaum, also of the university of california san francisco, robert dworkin of the university of rochester and once again my cohost dr. eric kandel a nobel laureate, and a howard hughes medical investigator. >> our subject is p
provided by: moving our economy for 160 years. bnsf, the engine that connects us. and by the alfred p. sloan foundation. supporting science, technology, and improved economic performance and financial literacy in the 21st century. and with the ongoing support of these institutions and foundations. and... this program was made possible by the corporation for public broadcasting. and by contributions to your pbs station from viewers like you. thank you. >> brown: a still tentative american economy looked online today, as digital deals were to be had, and holiday shoppers lit up web sites. retailers had high hopes that cyber monday sales would add to what's been a strong start so far. >> if all goes as expected, today will end up being the busiest online david year, with major bargains and steep discountses just a click away. >> every year we see more and more consumers shopping is online, both the younger computer born with a computer in their crib, and the elder generation is now also shopping online. deals are become, plentiful. >> all told the research firm comstore, estimates americ
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